Summary
I.D. Swiss Botanicals is at the forefront of innovation in neurocosmetics, integrating neuroscience at the heart of its products to understand and exploit the interactions between skin and brain. This approach allows us to discover how our mental and emotional well-being influences our skin. Neurocosmetics uses neuroactive ingredients to precisely target the skin's neuronal pathways.
The CBD VectorS™ is a multi-neuroactive liposome technology with dual encapsulation, designed to optimize their diffusion and efficacy. Used in Skin Stress Balancer serum, a dry, soluble product, this technology enables seamless integration into skincare routines without altering textures or fragrances.
Studies show that CBD VectorS™ has greater antioxidant capacity than vitamin E (α-Tocopherol) at low doses, with a reduction of 45% versus 29%. In vitro tests on reconstructed epidermis have shown that CBD VectorS™ improves skin repair, reduces inflammation and protects against various environmental and chemical stresses. In addition, CBD VectorS™ increases mitochondrial energy levels by over 300% and reduces skin sensitivity by up to 67%.
Research also confirms that CBD VectorS™ activates key physiological pathways such as Nrf-2 and TRPV1, enhancing protection against oxidative stress and inflammation.
By increasing cellular energy, reducing inflammation and protecting against various stresses, CBD VectorS™ represents a significant advance in neurocosmetics.
The future of cosmetics is moving towards holistic, science-based beauty solutions, harmonizing the interactions between body and mind. This approach promises to transform our skincare routine into a truly integrative and enlightened experience, opening up new horizons for health and beauty.
Introduction
I.D. Swiss Botanicals is an innovative brand in the world of neurocosmetics, integrating neuroscience at the heart of its products to explore the complex interactions between skin and brain. This approach enables us to better understand how our mental and emotional well-being is reflected on our skin. Neurocosmetics uses neuroactive ingredients to specifically target neuronal signaling pathways in the skin.
The CBD VectorS™ is a multi-neuroactive liposome technology with dual encapsulation, developed to improve their diffusion and efficacy. Used in Skin Stress Balancer, a soluble dry serum, this technology enables better integration into skincare routines without altering textures or fragrances.
Study results
A. Antioxidant study in tubo
The DPPH test is used to measure the antioxidant activity of the compounds. The results showed that the neuroactives in CBD VectorS™ possess greater antioxidant capacity than α-Tocopherol (the most antioxidant form of vitamin E) at low doses (EC50 = 1366 µg/mL).
- Antioxidant effectiveness :
- At 10µg/mL: a 45% reduction versus 29% for α-Tocopherol.
- Conclusion : superior efficacy to α-Tocopherol.
- Double encapsulation by CBD VectorS™ guarantees improved stability and bioavailability of neuroactive ingredients.
B. In vitro biomarker studies
Tests were carried out on reconstructed epidermis under cell culture conditions to avoid animal testing and invasive methods on human subjects. The efficacy of CBD VectorS™ was measured under a variety of stress conditions: UV/IR, urban pollution, and chemical irritation.
- Solar stress conditions (UV/IR) :
- Modulated markers : PDGF-BB , TNFα, TNFβ, TIMP-1, TIMP-2, IL-6SR, IL-8, CCL5.
- Results :
- Increased PDGF-BB, TIMP-1, TIMP-2, IL-6SR & reduced TNFα and TNFβ, showing improved skin repair and protection against extracellular matrix degradation.
- Increase in IL-8, indicating an increased but controlled immune response to repair UV damage.
- Urban pollution conditions :
- Modulated markers : TNFα, TNFβ, TNFRA, IL-1, IL-17, CCL24, IL-8.
- Results :
- Increase in CCL24 and IL-8, involved in the recruitment of immune cells to activate tissue repair.
- Significant reductions in TNFα, TNFβ, TNFRA, IL-1beta, and IL-17, highlighting anti-inflammatory properties in the face of environmental pollutants.
- Chemical stress conditions (SDS) :
- Modulated markers : IL-1α, IL-1β, TIMP-1, TIMP-2, PDGF-BB.
- Results :
- Increases in PDGF-BB, TIMP-1, TIMP-2, indicating a supportive role in skin repair.
- Significant reductions in IL-1α and IL-1β, demonstrating anti-inflammatory effects post chemical irritation.
- Basal activity (without stress) :
- Modulated markers : PDGF-BB, CCL5, CCL2, CCL1, IL-6sR.
- Results :
- Significant reduction in CCL1 and CCL2, indicating enhanced anti-inflammatory properties.
- Increase in CCL5 and IL-6sR, suggesting positive modulation of immune responses.
- Significant increase in PDGF-BB, implying an exacerbated functional state of cellular repair and an increase in mitochondrial energy levels of over 300%.
These results demonstrate that CBD VectorS™ offers robust protection against various environmental and chemical stresses, while improving skin repair and resilience, and reducing skin sensitivity by up to 67%.
In addition, CBD VectorS™, out of any external stress, appeases tissues (desensitizing effect) and guarantees additional energy resources (potential preventive and curative effects).
Promising prospects for neurocosmetics
Research from I.D. Swiss Botanicals illustrates strong antioxidant potential, an ability to increase cellular energy levels without associated toxicity, and positive impacts on inflammation and skin immune function under different conditions. The CBD VectorS™ activates important physiological pathways such as Nrf-2 and TRPV1, enhancing protection against oxidative stress and inflammation.
- Modulation of TRPV1 receptors :
TRPV1 receptors play a crucial role in temperature regulation and pain perception. By binding to TRPV1 receptors and acting on the endocannabinoid system, CBD improves skin condition and appearance by modulating cutaneous sensitivity and relieving irritation. This modulation reduces the perception of painful stimuli, offering a feeling of increased comfort for sensitive skin. It also helps reduce physiological responses to stress, contributing to an overall state of well-being.
- Activation of the Nrf-2 channel :
Nrf-2 regulates the expression of genes involved in defense against oxidative stress, essential for preventing skin damage and premature aging. Stimulation of this pathway improves regulation of antioxidant enzymes, protecting cells against damage caused by free radicals and environmental aggressions. This regulation also strengthens the skin's natural defenses, making it more resistant to external aggression. This cellular protection pathway is particularly essential for peripheral nerve cells, notably sensory neurons. Because of their high energy requirements, these cells produce large quantities of oxygenated free radicals. Over the long term, this activation reduces the harmful effects of chronic stress, ensuring greater protection and resilience for nerve cells.
Strengthening the neurocosmetic approach
The importance of neurocosmetics lies in the ability of its products to influence neurocutaneous interactions. The skin, as a major sensory organ, continually communicates with the brain via neural and chemical signals. By exploiting these pathways, neurocosmetic products, such as CBD VectorS™, go beyond traditional topical skincare by directly influencing the skin's neuronal responses.
Effects on mental and emotional well-being
Neuro-active ingredients such as those used in CBD VectorS™ have calming and soothing effects on the skin, resulting in reduced skin reactivity and improved sensory comfort. These effects are particularly beneficial for people with sensitive or reactive skin, where mental and emotional stress can exacerbate skin conditions.
Impact on neurocutaneous performance
The results demonstrated by CBD VectorS™ show a significant reduction in skin sensitivity of 67%, which is crucial for improving skin tolerance to external aggressors. By increasing mitochondrial energy levels by over 300%, CBD VectorS™ promotes cellular vitality, improving skin resistance and repair.
Holistic integration of beauty and health
I.D. Swiss Botanicals' neurocosmetic approach goes beyond improving the appearance of the skin. It also aims to harmonize the interactions between body and mind, offering a skincare experience that contributes to overall well-being. This holistic approach is essential to meet the needs of modern consumers seeking integrative, sustainable beauty solutions.
Conclusion
The CBD VectorS™ developed by I.D. Swiss Botanicals represents a significant breakthrough in neurocosmetics. By increasing cellular energy by over 300%, reducing inflammation and oxidative stress, and promoting tissue repair and regeneration, this innovative product demonstrates how a deep understanding of skin-brain interactions can be harnessed to improve skin health and overall well-being.
By integrating advanced technologies and neuroactive ingredients, skincare products can now target skin needs more precisely and effectively. The future of cosmetics is moving towards holistic, science-based beauty solutions that not only improve skin's appearance, but also overall well-being by harmonizing the interactions between body and mind. This approach promises to transform skincare routines into truly integrative and enlightened experiences, propelling the industry towards new horizons of health and beauty.
